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“We have also shown that they prevent the build-up of proteins associated with Alzheimer’s disease (at least in animal models), but the effect appears to be protective against future disease, rather than active disease.” Key takeaways “All of this points towards these drugs being protective for a number of diseases, many of which are driven by inflammation,” says Dr Cork

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aRWD: real-world data from cohort or registry studies (electronic health records, insurance-claims databases), bSRS: adverse drug reaction evidence from case reports and spontaneous-reporting systems, such as the Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) and World Health Organization (WHO) VigiBase