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The nuclear receptor FXR inhibits Glucagon-Like Peptide-1 secretion in response to microbiota-derived Short-Chain Fatty Acids
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Many studies have shown a U- or J-shaped relationship between BMI and mortality, where lower and higher BMI are associated with increased mortality risk compared to “normal weight” BMI levels (defined as a BMI between 18.5 to 25 kg/m²)
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