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GLP-1s and Addiction The authors of “ GLP-1 Therapeutics and Their Emerging Role in Alcohol and Substance Use Disorders: An Endocrinology Primer ,” appearing in October 2025 in JES, point out that the World Health Organization reported 890 million adults and 60 million children and adolescents had obesity in 2022 globally
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Constipation (19%), headache (18%), vomiting (11%), and dizziness (10%) represent the most frequent adverse events
