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In the Phase 2 obesity trial, the 12 mg weekly dose produced a mean weight reduction of about 24.2% at 48 weeks ( Jastreboff et al., NEJM 2023 ) — the largest figure reported for any single agent in the incretin class at the time
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[DOI] [PubMed] [Google Scholar] 61.Lubberding A.F., Veedfald S., Achter J.S., Nissen S.D., Soattin L., Sorrentino A., Vega E.T., Linz B., Eggertsen C.H.E., Mulvey J
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