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The Link Between PCOS and GLP-1 “In women with PCOS, insulin resistance and gut health imbalances may disrupt GLP-1 signaling,” says Jennifer Nicole Bianchini, MS, RD, IFNCP, RYT, a functional dietitian and mind-body wellness expert

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It is a major upstream driver of cirrhosis, hepatocellular carcinoma, cardiovascular disease, and chronic kidney disease