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Although the results of the trials were disappointing, some researchers say that GLP-1s could be more effective at treating Alzheimer's and dementia if they are taken before symptoms develop
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These discrepancies might be rationalised by the finding that the acute phase of GLP‐1 receptor‐induced ERK1/2 phosphorylation depends on PKA but a late, cytoplasmic phase requires β‐arrestin‐1 (Quoyer et al., 2010)
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