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GLP-1 Agonists and Pancreatitis - Med Ed 101
In the resulting IgG panel, the heavy chain complementarity-determining region 3 (HCDR3), which confers most of the binding activity and specificity, was found to include either a GLP-1 motif, a GLP-2 motif, or an unknown/unique sequence
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15 , 35 , 36 Furthermore, differences in hypoglycemic events were not substantial or reduced in combination treatment, suggesting that combination treatment does not increase the risk of hypoglycemia
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