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Naltrexone/bupropion (Contrave) Contrave is a combination of naltrexone and bupropion that is used for chronic weight management in obese (BMI 30 or more) and overweight patients (BMI 27 or more) in combination with a low-calorie diet and exercise
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tirzepatide is partly driven by the glucagon receptor component, which may cause greater GI effects at higher doses
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