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Dihydrocurcumin was highest at 20 min, tetrahydrocurcumin peaked at 1 h, and hexa- and octahydrocurcumin were highest at 2 h
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77 , 84 , 109 Semaglutide expands this profile by improving behavioural outcomes and altering amyloid load in both mice and human AD brain organoids, while also increasing oxytocin levels—suggesting additional neuromodulatory effects