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The hepatotoxicity of ethanol is primarily from metabolism to acetaldehyde, and by reducing ethanol metabolism from ethanol to acetaldehyde, GLP-1R agonism may be hepatoprotective, independent of a decrease in ethanol consumption 14
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Acute kidney injury: Dehydration as a result of prolonged vomiting may lead to acute kidney disease and worsening of chronic renal failure, which may require hemodialysis
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