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In preclinical models of NASH, the administration of AC3174, an analogue of exenatide, led to significant reductions in body weight, LFC, and levels of plasma alanine aminotransferase (ALT) and triglyceride [24]
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Like Lilly’s other tirzepatide medication, Mounjaro®, Zepbound is a dual agonist that mimics GLP-1/GIP hormones and promotes weight loss by slowing digestion, increasing satiety, and tamping down hunger